Research List

No.	Researcher	Title	Abstract	Year
2701	U Toe 1	PREPARATION, CHARACTERIZATION AND APPLICATION OF SPINEL MgFe2O4 NANOPARTICLE	The present research deals with a study on the preparation, characterization and application of spinel MgFe2O4 nanoparticles. The spinel MgFe2O4 nanoparticle was synthesized by sol-gel method using oxalic acid. Magnesium nitrate and ferric nitrate were used as starting materials. The elemental composition of the prepared nanoparticle was characterized by Energy Dispersive X-ray Fluorescence (EDXRF). The crystallite size, phase ID and lattice parameters of the prepared nanoparticle were characterized by X-ray powder diffraction (XRD) spectroscopy. The type of chemical bonding in the prepared nanoparticle was characterized by Fourier Transform Infrared (FT IR) spectroscopy, and porosity and morphology of the prepared nanoparticle were characterized by Scanning Electron Microscopy (SEM) spectroscopy. The energy band gap of the prepared nanoparticle was determined by the Tauc Plot method. The electrochemical property of the prepared nanoparticle was determined by the cyclic voltammetry method. The specific capacitance of the prepared nanoparticle was determined from the cyclic voltammetry graph.	2025
2702	Myint Myint Khin1, Nang Soe Htwe Khaing2, Tin Myo Khaing3, Aye Aye Tun4	PHYTOCHEMICAL SCREENING AND IN VITRO BIOACTIVITY INVESTIGATION OF CISSUS DISCOLOR BLUME (TABINDING MYA NAN) STEM	The stem of Cissus discolor Blume (Tabinding Mya Nan) was investigated for its phytochemical components and their bioactivities, including antioxidant, antimicrobial, and antiarthritic properties. A quantitative analysis was conducted to determine the phenolic and flavonoid content, which are known for their diverse bioactive potential. Antioxidant activity was evaluated using ethanol and aqueous extracts, demonstrating significant activity. Antimicrobial activity was assessed against six microorganism strains using the agar well diffusion method, revealing promising results. Antiarthritic activity was examined in vitro using the protein denaturation method, where the crude extracts exhibited activity comparable to standard drugs, with relatively high efficacy. The findings suggest that the antioxidant, antimicrobial, and antiarthritic properties of C. discolor extracts highlight their potential for developing enhanced traditional medicines.	2025
2703	Nwe Mar Lin1, Myatt Hla Wai 2, Sandar Aung 3	PREPARATION AND PHYSICOCHEMICAL ANALYSIS OF ECO ENZYME FROM CITRUS LIMON L. BURM. F. (SHAUK) FRUIT PEELS WASTE	Eco-enzyme, an organic solution derived from the fermentation of fruit waste, brown sugar, and water in a 3:1:10 ratio, offers a sustainable alternative to chemical-based solutions. In this study, Citrus limon L. Burm. f. (Shauk) peels were collected and fermented for three months. The resulting eco-enzyme exhibited a dark brown colour, a fermented aroma, and physicochemical properties including pH 3.9, total acidity 1.74 g/L, density 0.953 g/mL, and alcohol content 2.50%. Alkaloids, organic acids, glycosides, flavonoids, saponins, and phenolic compounds were present in the prepared eco-enzyme, contributing to its antibacterial and cleaning properties. The prepared eco-enzyme was successfully applied as a cleaning agent for ceramics and whiteboards. Wastewater samples from Nantawgone Quarter, Meiktila Township, were treated with the eco enzyme at concentrations of 5%, 10%, and 20% (v/v). The treatment effectively improved water quality parameters, including pH, total alkalinity, hardness, total dissolved solids, and chloride and sulphate contents. This study highlights the potential of eco-enzymes as an eco-friendly, cost effective solution for environmental hygiene and wastewater treatment while also promoting the recycling of organic waste.	2025
2704	Win Ko1, Mar Mar Win2	INVESTIGATION OF RADON CONCENTRATION AND TOXIC ELEMENTS IN WELL WATER AND SURFACE WATER IN MONYWA, MYANMAR	This study evaluates radon concentration and toxic element levels in water samples collected from various locations in Monywa, Myanmar. Samples were obtained from wells, rivers, and lakes, with radon concentrations measured using an LR-115 Type II detector and toxic elements quantified using an atomic absorption spectrophotometer (AA-7000, Shimadzu). The highest average radon concentration was recorded in well water used for drinking (30.02 Bq/m�), while surface water exhibited a maximum radon concentration of 13.94 Bq/m�. All measured radon concentrations were below the lower limit of the recommended action level. Additionally, the presence of toxic elements such as Cu, Zn, Pb, Cd, and As was detected in surface and well water. Radon levels in well water exceeded the EPA's recommended limit but remained below the WHO action level. Overall, the radon concentrations and toxic element levels observed in this study were within acceptable safety thresholds, providing valuable insights into water quality in the region.	2025
2705	Naw Yoon Eimzi Tun1, Hlaing Hlaing Oo2, Hnin Yu Wai3	SYNTHESIS, CHARACTERIZATION AND APPLICATION OF CALCIUM ALUMINATE NANOPARTICLES	In recent years, scientists have recently turned to the green synthesis of nanoparticles from solid wastes and used these in many applications. The calcium aluminate phase has been made by fusing or sintering together an appropriate mixture of CaO and Al2O3. These two metal oxides were investigated by using waste powder as raw materials. The key distinction in this research lies in the synthesis of calcium aluminate nanoparticles from waste quail eggshells and discarded aluminum cans (specifically, Coca-Cola cans) using the sonochemical method. The synthesis of calcium aluminate with two different weight ratios of CaO: Al2O3 (1:1 and 1:2), as well as different calcination periods and temperatures. The calcium aluminate (Ca12Al14O33) was synthesized at a calcination temperature of 1200�C, a calcination period of 1 h, and a 1:2 weight ratio of CaO to Al2O3. The average crystallized size of synthesized calcium aluminate nanoparticles was 43.82 nm. The antimicrobial investigation of synthesized calcium aluminate nanoparticles revealed significant antimicrobial activity against eight tested microorganisms. The inhibition zone diameters ranged from 20 to 29 mm. These results demonstrated that synthesized calcium aluminate nanoparticles hold potential as antimicrobial substances for other application fields.	2025
2706	Yin Yin Myint1, Pa Pa Lin2, Myint Myint Khine3	ASTAXANTHIN DIESTER AND MONOESTER FROM FRESHWATER PRAWN WASTE AND THEIR ANTIOXIDANT ACTIVITY	The major carotenoids present in prawn waste include astaxanthin complexes. Astaxanthin is a lipid-soluble, and orange-reddish carotenoid pigment. Two astaxanthin compounds, AS-I (astaxanthin diester, an orange oil, 1.84%) and AS-III (astaxanthin monoester, a yellow oil, 1.13%), were isolated from the ethanol crude astaxanthin extract of freshwater prawn waste using silica gel column chromatography with n-hexane-acetone eluents. The chemical structures of these isolated compounds were confirmed by UV-Vis spectroscopy, FT-IR spectroscopy, GC MS spectrometry, and visualization reagents, as well as solubility and Rf values. The antioxidant activity of the isolated astaxanthin compounds was evaluated using IC50 values. AS-III (astaxanthin monoester, IC50: 36.84 �g/mL) exhibited greater antioxidant activity than standard ascorbic acid (IC50: 47.48 �g/mL) and AS-I (astaxanthin diester, IC50: 263.53 �g/mL) as determined by	2025
2707	Khin Sandar Kyi1, Tun Zaw Moe2, Aung Chan Thar3	PREPARATION, CHARACTERIZATION AND APPLICATION OF PVA RICE STARCH-CHITOSAN BLENDED FILMS	Chitosan was prepared from shrimp shells and rice starch were extracted from rice grain. The polymeric films of PVA-rice starch-chitosan and PVA-rice starch-chitosan-glycerol-citric acid with various ratios were prepared by casting methods. The physicomechanical properties such as thickness, tensile strength, elongation at break, and tear strength of the prepared films were determined by mechanical testing. PVA-rice starch-chitosan-glycerol-citric acid films showed the potent antimicrobial activity on seven tested microorganisms such as Agrobacterium tumefaciens, Bacillus pumilus, Bacillus subtilis, Candida albicans, Escherichia coli, Pseudomonas fluorescens and Staphylococcus aureus by the agar disc diffusion method. Medicinal application of PVA-rice starch-chitosan-glycerol-citric acid films with various ratio was studied by using Wistar rats. After 15 days, the wound healing activity of the PVA- starch-chitosan-glycerol-citric acid film with the ratio of 2: 1: 2:0.5:1 was found to be effective on treated lesions of Wistar rats.	2025
2708	May Thazin Kyaw1, Aung Than Htwe2	PREPARATION AND CHARACTERIZATION OF CELLULOSE DIACETATE DERIVED MODIFIED MAGNETIC BIOCHAR FOR REMOVAL OF CHROMIUM(VI) IONS FROM AQUEOUS SOLUTION	Biochar (BC) derived from peanut hulls is a potential low-cost adsorbent for metal ions and organic pollutants, but its practical application is still limited by the adsorption capacity. In this study, cellulose diacetate (CDA) was prepared from waste cigarette filters by solution casting method. A cellulose diacetate magnetic biochar (CDMBC) and cellulose diacetate biochar (CDBC) were synthesized through chemical co-precipitation, with cellulose diacetate from prepared magnetic biochar (MBC) and biochar (BC). The morphologies, surface chemical structures, and crystallinity of the prepared BC, MBC, CDBC and CDMBC were characterized by SEM, XRD, TG-DTA, and FT IR. The adsorption of Cr(VI) ions by using different biochars as adsorbents was investigated under different adsorption conditions. Batch experiments were conducted to investigate the effect of metal concentrations, adsorbent dosage, time and pH values on the adsorption of Cr(VI). The Freundlich and Langmuir isotherm models were utilized in the analysis of experimental results to determine the optimal fit for the adsorption process of Cr(VI). CDMBC biochar showed the highest removal efficiency of Cr(VI) ions, attributed to enhanced surface area, active sites, and improved magnetic properties. In this research, the cellulose diacetate derived magnetic biochar could be used to remove the Cr(VI) ions in the environmental pollution of Cr(VI) contaminated waste water.	2025
2709	Thu Zin Tun1, Ye Myint Aung2,Yee Mun Than3	INFLUENCE OF PLANT LEAF EXTRACTS ON THE STRUCTURAL AND BIOLOGICAL PROPERTIES OF SYNTHESIZED MAGNESIUM OXIDE NANOPARTICLES	This research investigates the impact of different leaf extracts on the characteristics (such as morphology, size, and crystallinity) and biological activities (including antidiabetic, antioxidant, anti-inflammatory, and antacid effects) of magnesium oxide nanoparticles. The green synthesis of MgO NPs was performed using aqueous leaf extracts from Oroxylum indicum and Moringa oleifera as eco-friendly stabilizing agents. The synthesized MgO NPs underwent characterization through various techniques, including X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), UV-visible spectroscopy (UV-Vis), scanning electron microscopy with energy-dispersive X-ray analysis (SEM-EDX), and thermogravimetric analysis (TG-DTA) to assess their structural, morphological, and thermal properties. Biological studies assessed antioxidant activity using the DPPH radical scavenging method, while anti-inflammatory, anti diabetic, and acid-neutralizing activities were evaluated through egg albumin denaturation, ? amylase inhibition, and back titration methods, respectively. Results showed that both Oroxylum indicum and Moringa oleifera extracts produced MgO NPs with excellent structural and biological properties, but significant differences were noted between the two. This study highlights the critical role that the choice of plant extracts plays in green synthesis, significantly impacting the structural and biological properties of the nanoparticles.	2025
2710	Ei Pa Pa Zaw1, Jue Jue Khin2, Ye Myint Aung3	ISOLATION, PARTIAL PURIFICATION, AND CHARACTERIZATION OF ALKALINE PROTEASE ENZYME FROM SOYBEAN AND ITS APPLICATION	This study focuses on the isolation, purification, and characterization of alkaline protease enzyme (EC 3.4.21.63) from soybean. The enzyme was extracted using a Tris base buffer solution and purified through 30�60% ammonium sulfate precipitation followed by gel filtration chromatography on a Sephadex G-100 column. The purification process achieved a 3-fold increase in purity with a protein recovery rate of 5.8%. Qualitative confirmation of the enzyme was demonstrated using a ninhydrin test, while the enzyme activity was quantified at 2734.96 EU/g. Characterization of the enzyme revealed an optimum pH of 9.0 and an optimum temperature of 55 �C. Enzyme kinetics were studied, yielding an activation energy (Ea) of 4.553 kcal/mol, a Michaelis constant (Km) of 0.67 � 10?� g/mL, and a maximum velocity (Vmax) of 60.97 � 10?� mM/min using Lineweaver-Burk plot. The reaction order was determined to be first-order. The enzyme exhibited pH stability and thermostability under tested conditions. Finally, the potential application of the crude alkaline protease enzyme in the detergent industry was evaluated, showing its effectiveness as a laundry detergent additive. These findings highlight its practical utility in industrial applications, particularly in environmentally friendly cleaning formulations.	2025

Research Publications

Myanmar Academy of Art & Science List of Research