Research List

No.	Researcher	Title	Abstract	Year
1491	Myat Hnin Ei	EFFECTIVENESS OF SAPONIN ON PHYTOREMEDIATION OF PETROLEUM-CONTAMINATED SOIL	This study aims to evaluate efficiency of saponin, a natural surfactant, in remediation the soils which are smeared by crude oil and it was conducted based on the soil properties of oil ring no. (52), Nyaungdon Twonship, Ayeyarwaddy Region in 2019. For this purpose, soil properties were initially studied in this zone including soil texture, pH, moisture, nitrogen content, phosphorus content and potassium content. Crude saponin was extracted from the vegetable waste materials such as Onion (Allium cepa L.) skin, Ka Nyut (Asparagus officinalis L.) hard stem and Hin Nu Nwe (Amaranthus paniculatus L.) hard stem by the yield percent of 14.55 %, 2.53 % and 2.12 %, respectively. The studied phases included variables of saponin concentration within ranges of 250, 500 and 1000 ppm, contact time (10 week) and concentration of oil within ranges of 0.1-10 % in soil. The findings from assessment showed that the conditions under concentration of saponin (1000 ppm) on 0.1 % oil contaminated soil. The removal efficiency percentage of crude oil on 10 weeks contact time was observed 24.89 %. A laboratory study was extended to assess the potentials of local grass (Bermuda grass) under normal environmental conditions with or without surfactants in remediating soil contaminated with crude oil. The results of the phytoremediation of contaminated soil showed that significant reduction 76.3 % of crude oil was observed by natural saponin. It was also observed that the crude oil in the polluted soil was reduced by 72.4 % as a result of plant only, similar to commercial surfactant (SLES) treatment 72.1 %. This research indicates the soil remediation by Onion skin saponin, making better use of Bermuda grass and contributing to environmental protection.	2021
1492	Lae Lae Mon Win	PREPARATION AND CHARACTERIZATION OF CHICKEN FEET COLLAGEN FOR BIOMEDICAL APPLICATION	In this study, collagen was extracted from chicken feet and its biomedical application was investigated. The chicken feet were collected from poultry Myanmar market. The collagen was extracted from chicken feet by using acid solubilized method. The yield percent of crude was found to be 10.08 %. And then the crude collagen was purified by dialysis method, purified collagen was found to be 8.32 %. Both crude and purified collagens were characterized by using SEM, UV-visible and FT IR analysis. The SEM images of collagen to be regular and uniform with networking of porous on the surface. The absorption bands of crude and purified collagen were found to be near 230 nm in UV spectra. In the FT IR spectra, absorption bands of collagen sample indicated the presence of N-H, O-H, C=O, -CH2, -CH3 groups in the sample. The antimicrobial activity of both collagen samples were determined by agar well diffusion method. In this experiment, both samples were found to be high activities against six microorganisms such as Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus pumilus, Candida albicans and Escherichia coli, which showed that collagen possessed the high antimicrobial activity against all tested microorganisms. The wound healing effect of both collagens was investigated. It was found that the purified collagen was well-developed in healing of burn wound with well-developed sebaceous glands, sweat glands and hair follicles in epidermis layer of skin. This research therefore contributes to academics as well as biomedical application.	2021
1493	Nang Naunge Ying	PREPARATION OF SECRETED PROTEINS FROM STREPTOMYCES SP. SIREXAA-ETO HYDROLYZE CMC AND CELLULOSE	One of the insect associated bacterium, Streptomyces sp. SirexAA-E (SirexAA-E), was described to be highly cellulolytic. SirexAA-E grew well on cellulose and other plant cell wall materials such as xylan, and secretes a suite of specialized enzymes depending on the available carbon sources in the growth medium. Non-crystalline cellulose (CMC) and chemically pretreated miscanthus were used as sole carbon sources, and secreted enzymes were compared between two culture conditions. In the presence of CMC, several prominent cellulaseswere determined by SDS-PAGE. While in the presence of miscanthus, dozens of enzymes including above cellulases were determined, thus I decided to use miscanthus as a sole carbon sources to prepare the culture supernatant of Sirex AAE. The optimum condition of cultivation of SirexAA-E on miscanthus was determined with regard to protein yield (mg/L) and quality. It was confirmed that 5 days with 1 mL inoculum into 50 mL culture gave the highest protein yields with intact form of secreted proteins.	2021
1494	Nan Yu Nwe	APPLICATIONS OF MODIFIED CHITOSAN COMPOSITE MEMBRANES	The modified chitosan composite membranes (CASG-1 to CASG-4) were prepared with various ratios of chitosan, alginate, starch and glycerol by using casting and autoclaving methods. These membranes have smooth surfaces, highly transparent and pale yellow colour. The mechanical properties such as tensile strength, elongation at break and tear strength of these prepared membranes were determined. Based on the mechanical properties of the prepared composite membranes CASG2 was chosen for biomedical applications. The antimicrobial activities of prepared membranes were tested by agar well diffusion method. The skin irritation test was conducted by Draize�s method. The selected composite membranes (CASG-2) indicated that there is no irritation potential in albino rabbit skin. The selected composite membrane (CASG-2) was used to test in burn wound healing compared with standard sufre tulle drug. It was found that CASG-2 composite membrane was better than standard drug, sufre tulle for burn wound healing.	2021
1495	Hnin Yu Wai	PREPARATION AND CHARACTERIZATION OF POLYMERIC MATERIAL OF CELLULOSE ACETATE-POLYVINYL ALCOHOL FILM	This work is mainly concerned with the preparation of polymeric material from cellulose acetate with polyvinyl alcohol (PVA)) and glutaraldehyde as used as cross linker and the study of their characteristics. The films were prepared by mixing various proportions of cellulose acetate with various proportions of polyvinyl alcohol and fixed proportion of glutaraldehyde by blending, casting technique. The prepared films were investigated according to physicomechanical parameters such as thickness, tensile strength, elongation at break, tear strength and physicochemical parameters such as water uptake and swelling properties. The optimum ratios for preparing films were chosen according to their physicomechanical properties. The most favorable conditions for preparing film namely CPF 3 was found to be 20 mL of 2 % w/v cellulose acetate, 80 mL of 4 % w/v PVA and 25 mL of 0.025 M glutaraldehyde. It was found that the film CPF 3 possessed 27.30 MPa of tensile strength, 24.60 % of elongation at break and 58.90 kNm-1 of tear strength. All prepared films showed plain, clear, smooth surface, flexible, highly transparent and light white colour. The prepared films can be used in packaging materials.	2021
1496	Thwe Thwe Soe	FABRICATION OF ARECA NUT FIBRE-RUBBER COMPOSITES USING TAGUCHI OPTIMIZATION	In the present work, Taguchi method; a Design of Experiment (DOE) technique was used to optimize the process parameters to prepare the areca nut fibre - natural rubber composite possessing desired qualities, using minimum of time and resources. The tools and techniques such as, orthogonal array, signal-to-noise ratio (S/N), and the optimum condition were employed in Taguchi method to study the process parameters of the areca nut fibre - natural rubber composite. Three factors, namely fibre treatment type, fibre length and fibre loading (that is, loading of fiber) were considered as the process parameters. Three levels for each parameter were used. Accordingly, a suitable orthogonal array L9 (33 ) was selected and experiments were conducted. After conducting the experiments the mechanical properties (hardness, and tear strength) of the prepared areca nut fibre - natural rubber composites were measured and (S/N) ratios were calculated. With the help of graphs, optimum parameter values were obtained and the confirmation experiments were carried out, and satisfactory agreement was obtained.	2021
1497	Thazin Oo	PREPARATION OF SILVER COLLOIDAL SOLUTION COATED CERAMIC FILTER AND ITS ANTIMICROBIAL ACTIVITY	In this research work, the silver colloidal solution was synthesized by using silver nitrate and watery extract of bamboo leaves as reducing agents. The optimum ratio of red clay, brown clay and rice husk (6:3:1 w/w) were used for preparing porous ceramic filters. Silver colloidal solution was coated on prepared ceramic filter and silver coated filter, was obtained. EDXRF and SEM were used to examine the silver percent content of coated and uncoated ceramic filters. EDXRF analysis showed that silver (0.166 %) was present in coated filter and absent in uncoated filter. The antimicrobial activities of uncoated filter and coated filter by agar well diffusion method were tested on Bacillus pumilus, Bacillus subtilis, Candida albicans, Escherichia coli, Pseudomanas fluorescens and Staphylococcus aureus strains. The coated filter showed high antimicrobial activities on six microorganisms but not on the uncoated filter. Based on the results, prepared silver coated ceramic filters may be used as ecofriendly, environmental friendly and most effective filter material for water treatment due to its antimicrobial activities.	2021
1498	Theingi Win	Clay, Silica, EDXRF, FT IR, XRD, SEM analysis, standing method	In this research, the clay sample was collected from Khin Phone Chone Village, Kyaukpadaung Township, Mandalay Region. Elemental Analysis of the clay sample was determined by EDXRF technique. The extraction of silica from sample was performed by using various concentration of NaOH and HCl, 2 M, 4 M, 6 M, 8 M and 10 M. Then, silica was prepared from the sample using various stirring time and different temperature. For the sample, stirring time 60 min, 90 min and 120 min were used. By using different temperature such as 60 �C, 80 �C, 100 �C, the optimum temperature for silica extraction was chosen at 80 �C for the sample. The extracted silica was characterized by using EDXRF, FT-IR, XRD and SEM analysis. From EDXRF data, the highest amount of silica were found to be 81.892%. From FT IR spectra, the peak at 1052 cm-1 for extracted silica was indicated the presence of Si-O stretching. SEM image showed that silica from clay has amorphous nature. The adsorption behavior of extracted silica has been studied. Waste water from lead acid battery industry were treated with extracted silica by using standing method. Before and after treatment, the quantities of waste water were determined. After treatment, the percent removal was found to be 64.76% from sample (1) and 34.84% for sample (2).	2021
1499	Ohnmar Aye	ISOLATION, IDENTIFICATION AND CHROMIUM ADSORPTION BEHAVIOUR OF A CHROMIUM-RESISTANT PAECILOMYCES sp.	The present study was carried out to investigate metal resistant and adsorption strain. A chromiumresistant fungus M-1 was isolated from soil sample by conventional plating method. The isolated fungus was studied on the basis of morphological, microscopical characteristics and identified with the help of literature keys of Ando (2016). According to morphology and distinct characters, the fungal strain was identified as Paecilomyces sp. The fungal growth in metal resistant against Cr6+ ion at different concentration of 10 mM, 20 mM, 30 mM, 40 mM and 50 mM was studied. It was observed that Paecilomyces sp. was found to be resistant against 50 mM of Cr6+ ion. The biomass of chromium-resistant fungus was used for biosorption experiment by varying contact time and biomass dose. The biosorption of Cr6+ ion from industrial wastewater by chromium- resistant biomass showed 45.48 % removal and 1.9058 mg g -1 of Cr6+ ion at optimum contact time 8 h and biomass dose 0.4 g respectively. From the results, that Paecilomyces sp. showed chromiumresistant behaviour and biosorption potential for removal of Cr6+ ion from industrial wastewater.	2021
1500	Yi Yi Win	SOME CHEMICAL CONSTITUENTS AND SOME BIOLOGICAL ACTIVITIES OF PICRASMA JAVANICA FRUIT	In the present study, two compounds were isolated from the fruit of Piccrasma javanica and identified as 1-ethyl-4-methoxy-?-carboline and 1-ethyl-?-carboline on the basis of their spectroscopic data; UV, IR, 1H and 13C NMR in conjunction with 2D experiments (COSY, HSQC, HMBC) and comparison with published literature. For the cytotoxic effect of P. javanica fruit ethanol and water extracts; by brine shrimp assay method, the LC50 values were found to be 135 �g/mL for the ethanol extract and 318 �g/mL for the water extract. Moreover, the antioxidant potential of ethanol and water extracts was evaluated by DPPH radical scavenging activity, using ascorbic acid as standard and both extracts showed a good antioxidant activity with IC50 values of 7.71 �g/mL and 12.19 �g/mL, respectively. Total phenol content by Folin-Ciocalteu reagent method gave 43.06 � 0.5 mg GAE/g for the ethanol extract and 21.96 � 1.3 mg GAE/g for the water extract. Furthermore, the anti-inflammatory activity of the ethanol and water extracts by protein denaturation method was 44.44 % and 42.15 %, respectively, at a concentration of 1000 ?g/mL.	2021

Research Publications

Myanmar Academy of Art & Science List of Research