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No. Researcher Title Abstract Year
1121 Khin Ei Ei Thein PREPARATION OF PROTON EXCHANGE MEMBRANE (PSS) USED AS AN ELECTROLYTE IN FABRICATED DIRECT METHANOL FUEL CELL (DMFC) Membrane is one of the key performances for Direct Methanol Fuel cell(DMFC). A new polymer electrolyte membrane based on polystyrene sulphonated has been developed. In this research, the polystyrene sulphonated membrane was a casted product that obtained by the sulphonation of polystyrene with concentrated sulphuric acid. The polystyrene sulphonated membranes have been characterized by properties of ion exchange capacity, and water uptake as a function of molar ratio of polystyrene to concentrated H2SO4, FTIR, SEM and EDXRF. The S content of the prepared membrane was determined using titration method. Fourier Transform Infrared (FTIR) was performed to verify the sulphonation reaction on the polystyrene polymer. Morphology of the prepared membranes were characterized by Scanning Electron Microscopy (SEM). The chemical constituents of polystyrene sulphonated membranes were detected by using Energy Dispersive X-ray Fluorescence (EDXRF). At the optimal temperature of 40 ± 2?C for the time of 2 h, the optimal composition ratio of polystyrene to concentrated H2SO4 (w/v) was found to achieve as 1:2. The polystyrene sulphonated membrane has an ion exchange capacity of 0.79 meq/g and S content of 2.53 %. Therefore, the prepared polystyrene sulphonated membranes were suitable for the low temperature fuel cell, especially Direct Methanol Fuel Cell (DMFC) due to the range of ion exchange capacity 0.45-0.79 meq/g. 2020
1122 Thin Thin Nwe STUDY ON THE PHYSICOCHEMICAL PROPERTIES OF NATURAL SOIL FROM THE SELECTED AREAS OF LOIKAW TOWNSHIP, KAYAH STATE This study focuses on physicochemical properties of soils from the selected areas of Loikaw Township, Kayah State where many cereal fields have and the farmers always cultivate the subsidiary crops. In this work, soil samples were collected from the surrounding areas of Lin Phone Lay Village, Moh Pyar Village and Law Pi Ta Village in Loikaw Township, Kayah State at the depth of 0-6 inches in a zigzag manner. Physical parameters like moisture content, water holding capacity, pH, electrical conductivity, texture, organic carbon and humus and chemical parameters such as available P2O5, available K2O, total nitrogen, exchangeable Ca2+, Mg2+, K+ , Na+ , H+ and Al3+ were determined according to standard procedures. From this study, it revealed that the Moh Pyar soil sample was moderately acidic nature, Lin Phone Lay soil sample was alkaline nature and Law Pi Ta soil sample was neutral. The soil texture from Moh Pyar and Law Pi Ta soil samples were found to be sandy clay loam and Lin Phone Lay soil sample was silt loam. The contents of electrical conductivity, organic carbon and humus were found to be low level in Moh Pyar and Law Pi Ta soil samples. Among these three samples, the high content of macronutrients like available phosphorus (97.53) and available potassium (803 ppm) were found in Lin Phone Lay soil sample which were found to have sufficient value for agricultural use. The relative abundances of elements of selected soil samples were aslo analyzed by energy dispersive X-ray fluorescence (EDXRF) technique. The results obtained from this analysis revealed that seventeen elements in Moh Pyar soil, sixteen elements in Lin Phone Lay soil and Law Pi Ta soil were contained in these soil samples. The results from this research work indicate the types of soil as well as the nutritional values of selected soil samples needed for crop production. 2020
1123 Mi Mi Aye SCREENING OF SOME BIOACTIVITIES AND ISOLATION OF MANGOSTIN FROM GARCINIA MANGOSTANA L. (MANGOSTEEN) PERICARP The aim of present study is to screen some bioactivities and to isolate mangostin from the pericarp of Garcinia mangostana L.(Mangosteen). Firstly, the phytochemical constituents were investigated by the reported chemical methods. The qualitative elemental analysis was done by EDXRF technique. The extractable matter contents were determined by extracting sample with polar solvents such as ethanol and water. In the study of the antioxidant activity, ethanol and watery extracts were screened by DPPH radical scavenging assay. The ethanol extract (IC50 = 8.15 µg/mL) was found to be more potent than watery extract (IC50 = 12.3 µg/mL) in antioxidant activity. In addition, the antitumor activity of ethanol and watery extracts was investigated by Potato Crown Gall (PCG) test and both extracts exhibited antitumor activity with the doses of 0.15, 0.1 and 0.05 g/disc. Furthermore, the mangostin (0.09 %, 180-181°C) was isolated from the ethanol extract by column chromatographic separation technique. The isolated compound was identified by spectroscopic techniques compared with authentic mangostin. 2020
1124 Nwe Thin Ni BIOSYNTHESIS OF THE SILVER NANOPARTICLES USING TWO LEAVES EXTRACTS FROM E.ODORATUM (TBAGNPS) AND C. CITRATUS (LGAGNPS) AND ITS BIOLOGICAL ACTIVITIES The fabrication of silver nanoparticles by using watery extracts of Eupatorium odoratum L. (Taw-Bizat) and Cymbopogon citratus Stapf (Lemon Grass) leaves was mainly conducted. Silver nitrate was used as a metal precursor and two selected leaves extracts were applied as biomimetic routes of reducing agent for synthesis of silver nanoparticles (AgNPs). The surface morphology of fabricated silver nanoparticles (AgNPs) were performed with FESM (Field Emission Scanning Electron Microscopy). From the result of XRD (X-ray diffraction), the average particle size of TBAgNPs (32 nm) from E. odoratum and LGAgNPs (38 nm) from C. citratus watery extracts were observed. The size distribution of each prepared (AgNPs) was analysed by using advanced techniques Zeta potential-DLS (Dynamic Light Scattering). The localized surface plasmon resonance bands for formation of TBAgNPs (440 nm) and LGAgNPs (435 nm) in the ratio of 1:3 and 1:5 were exhibited in UV-visible spectra. The role of selected stabilizing agent of E. odoratum and C. citratus leaves extracts and the effect of stirring time on synthesis of AgNPs was reported. Furthermore, the laser beam of reflected rays as observed in the fabrication of AgNPs by the Tyndall effect. In addition, the antioxidant activities of TBAgNPs and LGAgNPs (49.27 ?g/mL, 94.32 ?g/mL) were determined by DPPH radical scavenging assay method. The antimicrobial activities of two kinds of leaves extracts and the prepared TBAgNPs and LGAgNPS were discussed against different strains of microorganisms. 2020
1125 Thin Thin Swe INVESTIGATION OF TOTAL PHENOL CONTENT AND ANTIOXIDANT POTENCY OF TAMARIND LEAVES This research deals with the study of total phenol content and antioxidant potency of leaves of Tamarindus indica L. (Magyi). The phytochemical investigation of tamarind leaves indicated that alkaloids, ?-amino acids, carbohydrates, flavonoids, glycosides, organic acids, phenolic compounds, reducing sugars, saponins, steroids, terpenoids and tannins were found whereas starch was not detected. Nutritional values of tamarind leaves determined by AOAC methods showed that tamarind leaves consist of 11.12 % of moisture, 3.56 % of fat, 18.67 % of fiber, 5.38 % of ash, 11.63 % of protein and 49.64 % of carbohydrate. The energy value of tamarind leaves was found to be 277.12 kcal/100 g. The extractable matter contents of tamarind leaves in petroleum ether, ethyl acetate, acetone, ethanol and water determined by WHO standard method. The total phenol contents of crude extracts were analyzed by UV-visible spectrophotometric method. The total phenol contents of watery and ethanol extracts of tamarind leaves were 24.70 ± 3.38 ?g GAE/mg extract and 13.30 ± 3.30 ?g GAE/mg extract. Antioxidant activity of tamarind leaves was also investigated by using DPPH assay. The IC50 values of watery and ethanol extracts of tamarind leaves were observed to be 57.13 ?g/mL and 34.47 ?g/mL, respectively. The ethanol extract is more effective than watery extracts in antioxidant activity. All extracts showed mild activity when compared to the standard ascorbic acid (7.97 ?g/mL). 2020
1126 Yoon Noe Aung ISOLATION AND FERMENTATION CONDITIONS OF SELECTED SOIL BACTERIUM (YN-51) FROM LAPUTTA TOWNSHIP AND THEIR ANTIMICROBIAL ACTIVITIES Soil samples from three different areas of Laputta Township, Ayeyawady Region were cultured on five kinds of media. A total of 79 bacterial colonies were isolated from these soil samples. The purpose of this study was to screen for antimicrobial activities and fermentation conditions for selected bacterium. In this study, antimicrobial activities of all isolated strains were examined by agar well diffusion assay with seven test organisms. Among them, ten strains namely YN-1, 6, 7, 35, 51, 55, 56, 57, 59, and 63 showed different levels of antimicrobial activities. Especially, YN-51 showed the highest activity on Candida albicans. The fermentation conditions of YN-51 were optimized by the studies of fermentation period, proper size, age, different carbon and nitrogen sources utilization, pH, temperature, static and shaking culture on antimicrobial metabolite production on Candida albicans. In the fermentation period, YN-51 showed the highest activity (22.31 mm) in 3 days followed by (21.82 mm) in 2 days against Candida albicans. In the investigation, YN-51 was found that 15% of size of inoculum and 72 h of age of old culture were suitable conditions. The addition of glucose as a carbon source resulted better growth of YN-51 and the inhibition zone reached 27.07 mm in sucrose. In the nitrogen source, the maximum growth of YN-51 was found in yeast extract and the highest antifungal activity (30.49 mm) was found in beef extract. And then, effects of pH range and temperature were also determined. According to the results, pH 7.5 and temperature 40 °C were found to be the best activities (29.64 mm and 27.29 mm) on Candida albicans respectively. In the comparison between shaking culture and static culture, the antifungal activity reached (25.61 mm) in shaking culture and (21.70 mm) in static culture respectively. 2020
1127 Moh Moh Aye PRELIMINARY PHYTOCHEMICAL INVESTIGATION AND SCREENING OF ANTIMICROBIAL AND ANTIOXIDANT ACTIVITIES FROM THE STEM BARK OF CROTON OBLONGIFOLIUS ROXB. (THAK-RING-KRI) Croton oblongifolius Roxb., a middle size tree as medicinal plants, was chosen to investigate phytochemical constituents, nutritional values, screening of antimicrobial, total phenolic contents, total flavonoid contents and antioxidant activities. Preliminary phytochemical investigation of Thak-ring-kri bark revealed the presence of flavonoids, phenolic compounds, glycosides, saponin, terpenoids, steroids, carbohydrate, tannin, starch and ?-amino acid. Alkaloids and cyanogenic glycoside were not detected in the sample. The AOAC method was used to determine the nutritional values such as moisture, ash, protein, crude fiber, fat, carbohydrate and energy value. The content of these values are 6 %, 10 %, 5.73 %, 11.45 %, 7.43 %, 59.4 % and 327 kcal/100g, respectively. The antimicrobial activity of pet-ether, dichloro methane, ethyl acetate, ethanol, methanol and watery extracts was determined by agar well diffusion method against six species of microorganisms such as Bacillus substilis, Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus pumilus, Candida albicans and E. coli. It was found that all extracts showed antimicrobial activity against all tested microorganisms. Its watery extract showed less activity (12 mm) and pet-ether extract was observed the most pronounced antimicrobial activity (16~35 mm) against all microorganisms tested. Total phenolic contents was determined by spectrophotometric method using Folin-Ciocalteu reagent. Ethanol and watery extracts of the total phenolic contents were found to be (197.50 ± 0.01) µg GAE/mg and (41.42 ± 0.00) µg GAE/mg respectively. Total flavonoid contents was studied by spectrophotometric method. The ethanol extract contain flavonoid content (115.34 ± 0.01) µg QE/mg higher than watery extracts (70.00 ± 0.00) µg QE/mg. From the screening of free radical scavenging activity of Thak-ring-kri stem bark by DPPH assay, it was found that ethanol extract (IC50 = 5.9 ?g/mL) showed the higher radicalscavenging activity than watery extract (IC50 = 18.5 ?g/mL). 2020
1128 Khin Myint STUDY ON IN SITU REMEDIATION OF CONTAMINATED SEDIMENT FROM FLOODED AREA OF MINBYA TOWNSHIP, RAKHINE STATE This research is concerned with the remediation of contaminated sediments from the flooded areas, Middle Lake and Small Lake of Minbya Township in Rakhine State.The two sediment samples were collected in September, 2018. The investigative analyses were done in terms of distribution of some heavy metals in the sediment samples and microbiological properties of sediments. Relative abundances of elements in the sediment samples were determined by EDXRF. The quantitative elemental analysis of the sediment samples were determined by AAS. Cadmium concentrations of the both sampling sites were not detected and those of arsenic , iron and lead were (0. 14 , 0.15) ppm, (24.17 , 24.57) ppm and (0.09, 0.23 ) ppm, respectively. Microbiological properties of sediments were examined by using 3M Petri Films. Total Coliform could be observed as (3000) and (9000) cfu g-1 in these study areas. However, E.coli could not be detected in both sites. Overall values of study areas indicated that the iron was in high level in the contaminated samples. The in-Situ treatment system for contaminated sediment was treated by using lime amendment and sand-cap. The cost effective in-situ treatment system has shown the significant removal percent of iron (50.29 %) to (50 %) compared with control (without amendment) system. This remediation technique code inferred the very beneficial for rural area as in cost effective and locally available technique. 2020
1129 Nyein Nyein Htwe ISOLATION OF BIOACTIVE COMPOUNDS FROM BARK OF MIMUSOPS ELENGI ROXB. (KHA-YAY) USED IN THE TREATMENT OF HYPERGLYCEMIA The present research focused on the investigation of antihyperglycemic activities of two crude extracts (70 % ethanol and water) and isolated organic compounds from bark of Mimusops elengi Roxb. (Kha-yay) by using adrenaline induced hyperglycemic rats. The optimum antihyperglycemic activities of two extracts showed 70 % ethanol extract (30.11 % reduction, p < 0.01, 1 h and 35.25 % reduction, p < 0.01, 2 h) and watery extract (19.94 % reduction, p < 0.01, 1 h and 21.61 % reduction, p < 0.01, 2 h) after treating with 2 g/kg body weight dose. Lupeol (0.0037 %, m.p- 215-217 °C) and spinasterol (0.0048 %, m.p- 167-169 °C) were isolated from pet-ether soluble portion of 70 % ethanol crude extract by column chromatographic method using pet-ether and ethyl acetate with increasing polarity ratio as eluent. Both compounds were identified by modern spectroscopic methods (UV, FT IR and 1H NMR) and confirmed by comparison with the data reported in literature. Reduction percent of blood glucose levels of lupeol and spinasterol with a dosage of 2 mg/kg body weight showed 19.44 % (p < 0.01) and 22.01 % (p < 0.01) at 2 h respectively. 2020
1130 Khin Myo Myint Tun TOTAL PHENOLIC CONTENT, TOTAL FLAVONOID CONTENT AND ANTIOXIDANT ACTIVITY OF CLITORIA TERNATEA L. (AUNG-ME-NYO) FLOWERS In the present research, the flower of Clitoria ternatea L. (Aung-me-nyo) that is one of the most popular Myanmar medicinal plants was selected to study total phenolic content, total flavonoid content and antioxidant activity. Preliminary phytochemical analyses indicated the presence of alkaloids, glycosides, carbohydrates, phenolic compounds, saponins, tannins, ?-amino acids, reducing sugars, steroids, flavonoids, anthocyanins, starch and organic acids. Total phenolic contents of various extracts were investigated by Folin-Ciocalteu reagent and total flavonoid contents were determined by aluminium chloride colourimetric method. According to the results, total phenolic contents of petroleum ether, ethyl acetate, methanol and aqueous extracts were 16.36, 33.16, 25.12 and 11.22 µg GAE/mg of extract, respectively. Total flavonoid contents of petroleum ether, ethyl acetate, methanol and aqueous extracts are 132.17, 86.52, 73.48 and 23.48 µg QE/mg of extract, respectively. Antioxidant activity of the extracts of Clitoria ternatea flowers was screened by DPPH assay method and powerful antioxidant activity of the flower extracts was observed. 2020