Abstract

• Escherichia coli is known to cause several infectious diseases such as urinary tract infection and gastrointestinal disease. Marine endophytic fungi from marine sponges have potential as source of new compound against Escherichia coli. In the present study, two marine sponges were collected in Shwe-Thaung-Yan coastal area for the isolation of marine fungi on August, 2018. The isolation was undertaken by surface sterilization method. In this study, seven endophytic fungi were isolated from two marine sponges. Among these isolated fungi, two isolates, SF-04 and SF-05 showed antibacterial activity against Escherichia coli. According to fungi identification results, fungus SF-04 was identified as Trichoderma sp. and fungus SF-05 was identified as Aspergillus sp..